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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01aa1bedcf3b66855451af81371fa56258eb0aeb21fa178bfb3dfe9f81835fcd' 
  AND token = '2na6X5Da+FyhC4aSOYYhXZSLfrjUGtatYqbRViJ9EA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}