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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e038630b2fdea605ed538f4362c0c23eb8b5ec660b9fb513a1f7c289b29e501' 
  AND token = 'DrRxFmMfDp3fvdmobfCj8/Md+S80wJ1GqHVfmoQUw10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}