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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8c7e5e0e53054a770ab3bd3a98beedab5cdbb288599122e299def7d9a65786a' 
  AND token = 'S2b7lwENuEGcojeUzSpeL/lVYEB1mmuER1CwCtd93Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}