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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43ac90fd7226790b3bee1224ba37632b92b231720437c0a1fe2d6a1591991d0' 
  AND token = 'mkCdZ5WfadUBEvIz6Cq65FLwDjQUaZI15QW3DyEgyqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}