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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a41672770efed234b89a2a7f027e111c53817373f605c67cc5e3242d195cd462' 
  AND token = 'TUx5FSlK3fp4cO8NYGAjv9wAVtTwAVn5/6sF4W2zM4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}