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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2862acbdc0e68a097398706e1477489263a8fc7c3e5944df9977da6c3eef7946' 
  AND token = 'FsEXfWeDgkN1rN5duA86CYe9TGAdFw/Rtsf9EmqYCAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}