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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '917a6a57189f63cb5b10d632f0b79814c2c5aefffd7f0fa4c2293e047385dad3' 
  AND token = 'dIgO5DDWb4e2d2Rrdr9AxcNOfduj5MCV4nSJ7wUYz4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}