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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe88a5ec1f5800bbd05daf8ba43295201acb28d5a5eb58af4194c2a481991443' 
  AND token = 'tSFmGeEIGNOEpIbscGgQSxPoolujzb5VirGVzxbBjRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}