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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '426cce74feabfaf72dcb74f62eaf1ea24b386e5c4cecd3c441e83eb551df0e2d' 
  AND token = 'RFn8sw4gi8RIk470NFXXDWfv0mH3P+Wf7dJEuYMm2DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}