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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '200c9fe2be69f3e4c9672fd5360385f0abb341a7f37f213928e4f7fca8a15f9a' 
  AND token = 'Qy2VFDZ0fPDdgQdaXa5eAJohksfniqZ1H3gKIQL8qxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}