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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a78a1d98ddcc350c6b0c660410173d07deb8c821247e4d8a9ee1d27249148f1d' 
  AND token = 'XXrjB5JCibvmrMM6tdWFvpoqZbixBdGpK8TSnO5CBRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}