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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '020c438dc3a59175ea2cc67901e3469ce999021d2f567c304e102103a263cc05' 
  AND token = 'KsCPrRaOelneiDq4etexy1TbO/qSQvFSAF0YljFhVE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}