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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f94ec29f5f19d943b456af27bebe02de1f0994ab8a2fdc344b6f4623749151' 
  AND token = 'pTRL8PVvtWDwhXqntKhbexTXFAoJ1s8esItWHy78yhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}