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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9727cee8474295f9327266b1d7f216f3cbdbba8822ec09d9368717d5c9552600' 
  AND token = '7lZjm97pTfxjZQL0NkK60prIyB0VG++Q9JHgflWQbNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}