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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '144ae0ae43457159e467b9e9175b0de38ee29e752a65b24378bbe66c6a9f2433' 
  AND token = 'kG0FE1p+7m/eN1a8aw9N25AjkDfv3QVL9C0RptyyDqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}