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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381150e6b821f6a26e52b02877a15e2f638dd1e90fa932657c7a3e13bd16f8b2' 
  AND token = 'Ogv9bqahYqYmss4xpJZEzKPp8K1WEIefqgFnMk2hl5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}