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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a744c29eb2d87a4baca611c19e2aadb60ccaa686fcff17550befe01ed18179a' 
  AND token = '3mr2SPoxb/kNDEhlmFAbxpSvAILh2TjA7OUQ6/mkBk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}