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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a535d47f04f32f80dab11c4b215a5306d527adfcabfb96a3f3d2121e27fca13' 
  AND token = 'Cgwi8Sty2bx5AO/KIql5xWEGUxegsHf68vqDcpqD66c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}