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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd05d79064362d66d6d3ae7ebc472da63e6a0c4cc22bf01ec4ce0881c94634e45' 
  AND token = 'JZeyLE05MH+IXZuTB3f61/iCZbl9Uzc+VVkbUeUm8f4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}