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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b1a45210b5524a49dde36d158ac61689707ab49fe3780580056cbdd4f4d6f96' 
  AND token = '/a6EvVUMSIWLZ7sKiBNJwewnEUOJMS+9YkfeP1DAxvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}