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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5194506a2535f35d3c409e277ee20e51f72008eb208549c9d4788d638e0576c3' 
  AND token = 'yH7bg76Pv59a5zJ+VlMw8YzOVWy2tIGuWrA5yUbQp24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}