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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc66a49e6f5a68aa9455aede0b43720bed1a8fc9184b40a31b736d77e7dd381c' 
  AND token = 'qI0BRAexJE7aGTOdX7Y2ejnhId3+D9YMZHeCxPo8ucU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}