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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4128e877c5f1ddd98495b11007aa01638f645e9cdaa0da87b124f9ee5ff67a41' 
  AND token = '1c8rKIADO4BFNv+ga1Cdexd4CgQQdlJ0FZAOr3XS04Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}