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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06a0f2431a1ec3ea2c9401c9c47f2470666360a0a1c185ce7402699767b52998' 
  AND token = 'BPx0cJXf5wCoEKyt5dGaeYm7RxeuGzsXBJHUYZqvxvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}