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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6daa4f00e769ada14ec3ff45c5c35154de1a20739eb84769368b9b4b3945af41' 
  AND token = 'wrxU4Mdwh+6EjA64CiMNV9c6sTapmyMcsWLq7Wvbu5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}