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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '377cf3903434857b6a49999499045b72b08c9c1f2e24482917ca2c81e99bc7fd' 
  AND token = '6ltxGOinFhPgp+B5XwEbUeUCeoGifzg2o5keJWoMs6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}