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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93a6dc0c56a350aaf27923f8e20d51d9700a49049f38a2e46caafccd27134e01' 
  AND token = 'cZ+kyDxYInoe+L57NYQMLscLXtgrXMpGf0c2AVphFpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}