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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afca8506de9f69628de96f1011ab1cd63a1462caa44ad4a1d282f2ef6a493298' 
  AND token = 'oaZ5XXwhbxHRJa3fmKZDrpUra+48/ArugA7qcQJSLZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}