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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ced3525e31cb648932dd8d6f433b0d88156d31a2a34c3a25ff2ec15956568c45' 
  AND token = 'OFoSqV2o8DWcr2MWyMFYbX09ScSXjr3+YdxpW30s1b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}