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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae0eaab8b0188d0b3c80b11589d785ad44ea3e87767dba8310628569de294a88' 
  AND token = '5ecxyo+X8W1wIFytE6eHuFhsVlrsTV6OJQ2JF33xdtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}