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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '467ea7b75dc406658f1d11133079644aed1966620eef40e6dbafc0f2ae9b2255' 
  AND token = 'lFj/GJ8bQtJLO3Sb7FSUd9sWiTKEGfms/LS71BDepXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}