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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8e9883955d38ef3c0e8d7f8e9468fa13cb18c2051955f3979b0339905fdf97' 
  AND token = 'w9TaPaWYqJWd8FvmvO+vhrPfI1cq6vIgG9pJT4F8UJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}