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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '974debf1e6ca176e5c8d8dce04d372ff72228b4d7601d7564cc8ed29c9b2b86d' 
  AND token = 'Nnt/mElD505W7+VZP3aW3+4XTVBdmnH54tzWZNr0Rrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}