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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '294bb927e5a8363e5916fe841919d45b741e62f64a7e8b6fdc795d5d87d6f2cd' 
  AND token = 'TeLdStwb8HSI30/xBW0jBzikgQHc2BLbqxiw2u4BPKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}