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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecab586342e37e9089c1173b1dcd7c65f11bf54dfe9c985d09ec0343db929e2d' 
  AND token = 'RddDl6Aj0EePuwTfppT6YHz8A8Wpy4I2UNffBiJ/FNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}