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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '478663e3b8d58b1664d3941c46b13aa2ef8b2327fb3ea18c2edc51abe73b692c' 
  AND token = 'rv3E7acoA96T/Z4hCLqmwlo0wF0fVyO7rnFF/mL5Zjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}