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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3751f9845cd6a66627370e157f009218a69ec94f6e73d962a73834ad254baa96' 
  AND token = 'yz2zEFgZWKqM8dSBcK6uiqzqeadwBpy7ZWpIB/aKxjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}