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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6cb79834d14018e2ed0d423deaf73da443c8798bc6ce57323dd5f34212b381b' 
  AND token = 'JY61pSaWtVCU2iaDAiZsB0OS3cpxy2XDoNBHtASv6eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}