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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '627ca211c3520c3f4a58a1afe01d3f88387b1d275486499c17c167881bbca393' 
  AND token = 'QbWDceEIj4bPKqoTLEd7ujShFVFs0uJ0KVwvcPrNKBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}