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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168b35c37a1c05b1780190bc9dcc3576c87cd11a054484567495e1353849612a' 
  AND token = '2661XHsacG4FOxm8J+fFC6S6crXL5+7qiXspynLI6nM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}