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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77433a829063e0d62b63f260dbe77d05093f2e7195851045139264d27ec91e8c' 
  AND token = 'Sn3gQM02KFKRepTv+IFvopSk+nv/H7Hi6zSqnuUeOYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}