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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd66b5112f4790f558ed68435c43b1296af1dad0133646afeb16db1fb347eec42' 
  AND token = 'Pqs5ow7LEkJTnkSgUNZxTOm03jpN59JWl23SkeIb+1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}