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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38a53ef2f5ff7d8016165ba4d4c4ea87a09906239c733cac7d9af6183cd781b2' 
  AND token = 'a2GBQLjp4w4Clyd9n4LnOCCf/xLhg6HVJ4cnM2lQhuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}