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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8789ea1d60b7c59d5759776e5860254f60eef1d223d4455a307a5c5f7c54f3b9' 
  AND token = 'NrG/qrCngjk8LNqBgpOtCO9UesmtOoUByS72doeQcio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}