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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f013c7a4e7a0006dd1748cd281620b4f27d23b9253ecbeab179c1ab74a23f14' 
  AND token = 'z1qEYFJ6yzjuxjihHgnVCw1Lc6Ws0U52MAIbcu34uqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}