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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7761bc16189e2d9a1e047a499a2b275af16bb38ac3cdb21b5c6a4995015fe6d2' 
  AND token = 'xbIgfdHJfjwqUgywl628+6v5Hjqt5RBO8CirTAlRCYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}