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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e3e71515f297a78e08a7d7dda3e83369b6722eaa65b7775690ac30dd8edeb3f' 
  AND token = 'w1fBUA7N2+C7BWmRqg7BcUQ1LGYulMyU6DrfZdm3BB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}