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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c19a2d6653fbe2473fe012095511b63c6576c2013e6d56f901b2a418ea7d3e0' 
  AND token = 'qCnzlq/ENr+ZHjGqn9y5yUxtEMdeBnlMn9GBP3Xwc28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}