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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372d047f1c0070ce1d577c6eec7de2905f501035b9c81d8a1dd7ffa81a20d17b' 
  AND token = 'M88s9Qs1NwKTB9SQtYGAgz9DU7uQyLuZOs3IXy3+g1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}