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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45971fa9fc51a391ae2f4456bac8fa4d22f43b272839c30340d5264c2b2379d9' 
  AND token = 'u5s5cOH2f9k6SfHAQCuIVqQjODpXpjRecLCSD8DJtVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}